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Infection with #SARSCoV2 has highlighted how altered endothelial functions contribute to multiorgan health effects during the acute phase of #COVID19 and potentially to the longer-term consequences associated with #LongCovid. Learn more in a new #SciencePerspective: https://scim.ag/3OOaaCM

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A new genomic study in Science encompassing more than 300 genomes spanning the last 50,000 years has revealed how a single wave of Neanderthal gene flow into early modern humans left an indelible mark on human evolution. scim.ag/4gkMvpz https://scim.ag/4gkMvpz

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Breaking news: A 2020 paper that sparked widespread enthusiasm for hydroxychloroquine as a #COVID19 treatment has been retracted, following campaigning by scientists who alleged the research contained major scientific flaws and may have breached ethics regulations. scim.ag/4iR9bQ6 https://scim.ag/4iR9bQ6

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Earlier this year in Science, researchers generated a nanoscale-resolution reconstruction of a millimeter-scale fragment of human cerebral cortex, giving an unprecedented view into the structural organization of brain tissue at the supracellular, cellular, and subcellular levels. scim.ag/3BjR7xa

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“The academic structure … makes planning for a family feel like an impossible luxury.” In this #ScienceWorkingLife, two postdocs share how, as women in academia, having children can feel impossible—and how talking about it makes them feel less alone. scim.ag/49BKZgp

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A species of lungfish found in South America has claimed the title of the animal with the biggest genome sequenced so far. Learn more: scim.ag/4gEQU6n https://scim.ag/4gEQU6n

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Every weekday, #ScienceAdviser delivers the world of science to your inbox, keeping you up to date on the most important trends and breakthroughs. 📥 Sign up for the award-winning #newsletter: scim.ag/4fgFSmX https://scim.ag/4fgFSmX

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In a new #ScienceSignaling study, researchers introduce extracellular #TurboID, a refinement of the popular proteomics tool that interrogates #ProteinProteinInteractions on the exterior cell membrane, and characterize interactions between #EGFR and #LDLR. scim.ag/3DgfJr9 https://www.science.org/doi/10.1126/scisignal.adl6164

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“In naming … lenacapavir as the 2024 #BOTY, Science acknowledges the next, but by no means final, step in the drive to fight HIV/AIDS, where the rigors of the laboratory and the needs of humanity are inseparable,” writes @holdenthorp.bsky.social in this week’s #ScienceEditorial. scim.ag/4g9kjG4

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Science’s 2024 Breakthrough of the Year is lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months. Learn more about this year’s #BOTY and other big advances in science: scim.ag/3BrCtUn